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Baclofen is a drug that has a long history of use as a treatment for spasticity and spasms in multiple sclerosis. Baclofen is taken by mouth (orally) as tablets or as a liquid. Treatment usually starts with a small dose that can be increased in steps until it is most effective or side effects become a problem. It’s recommended that you take the tablets with food or a milk drink to reduce the chance of experiencing nausea.

Other names for this medication:
Baclofen, Lioresal, Baclofene, Baclofeno, Baclon, Baclopar, Barambo, Clofen, Kemstro, Liofen, Lyflex, Miorel, Pacifen,

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Baclofen is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by medical problems, such as multiple sclerosis or certain injuries to the spine. Baclofen does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Baclofen acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects. Baclofen may also be used to relieve other conditions as determined by your doctor.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet
  • Solution
  • Powder for Suspension

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Genetic diversity of Forest and Savannah chicken populations of Ghana as estimated by microsatellite markers. We report a 79-year-old man with the coexistence of both conditions.

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An organ and effective dose study of XVI and OBI cone-beam CT systems. These mutations effect ameristic male development in the presence of ACE but have no effect on hermaphroditic development. The long-term delivery rate among women with a first ectopic pregnancy has improved significantly over time. Effect of replacing glucose with lipid on the energy metabolism of newborn infants.

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When cultured under permissive conditions (33 degrees C and in the presence of gamma-INF) cells isolated from H-2Kb-tsA58 mice express the large T antigen, which drives the cells to proliferate. The cue-target stimulus-onset-asynchrony (SOA) was varied to assess the time course of the attentional effect. N-acetylglucosaminyltransferase III (GnT-III) catalyzes the formation of a bisecting GlcNAc structure in N-glycans, resulting in the suppression of metastasis.

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Indomethacin (1 microgram/ml) completely suppressed the release of PGE2 by alveolar macrophages. The results show that both fluoxetine and melatonin decrease the signs of depression and anxiety in all tests. Multiple regression analysis in kidney transplant recipients showed that hepcidin was independently related only to GFR and ferritin. Contacts across the Strait of Gibraltar in the Pleistocene have been studied in different research papers, which have demonstrated that this apparent barrier has been permeable to human and fauna movements in both directions. We describe whether the health benefits from the increased physical activity of a modal shift for urban commutes outweigh the health risks.

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Twelve tubo-ovarian allografts using cyclosporine for immunosuppression resulted in seven viable grafts and three pregnancies. The concentration of purines in plasma and urine from a 37-yr-old healthy man with a very low plasma urate concentration was measured by HPLC. By means of this system blood pressure measurements were made in five healthy male subjects watching a match of the Dutch National team at home, during the 1988 European Championship. The role of a new syringe filter in harm reduction: the views of active injection drug users

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Fulminant hepatic failure is a rare complication of status epilepticus. Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents.

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Because of the very fast elimination of glucuro-conjugated drugs, this observation required intratumoral injection. The assessment of the prognosis of musculoskeletal conditions in older adults presenting to general practice: a research protocol. Finally, the importance of teamwork especially in terms of cohesion and communication is highlighted. Description of the natural course of VAP resolution and multivariable analyses of predictors of VAP recurrence and death by day 28 after VAP onset based on the 401 patients included in the PNEUMA trial, a multiple-center, randomized study comparing 8 vs. The exact sequence of events in Acute Respiratory Distress Syndrome (ARDS) is unknown, though increased permeability (pulmonary edema) is the primary physiological abnormality seen in the early stages.

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Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine favouring the secretion of TNFalpha and IL-8 and counteracts anti-inflammatory effects of corticosteroids. Enhanced salt and water reabsorption is demonstrated in distal nephron segments irrespective of the stage of gestation.

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We have previously suggested that CD4 interacts with the T-cell receptor for antigen (TCR) and with class II MHC and that this dual interaction stabilizes the bond between the TCR and antigen in association with MHC. These give new insight into the coupled singlet-triplet dynamics of SO2.

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Inhibition of tumor implantation after laparoscopy by specific oligopeptides: a novel approach to adjuvant intraperitoneal therapy to prevent tumor implantation in an animal model. The study was based on data available from the National Institute of Mental Health Treatment of Depression Collaborative Research Program (1982 to 1986). The golfers who experienced yips could be categorized according to whether they reported mainly movement-related symptoms (Type I) or anxiety-related symptoms (Type II). The actin multigene family in Populus: organization, expression and phylogenetic analysis. Photodynamic therapy with verteporfin combined with intravitreal triamcinolone injection in the treatment of neovascular AMD may be superior to PDT alone by decreasing visual loss and reducing the number or retreatments.

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The inner surface of the bulbus wall is irregular due to the presence of branching ridges that flatten and disappear toward the ventral aorta. Results of the three-year surveillance by the Italian SALM-NET System: human isolates of Salmonella serotypes.

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Epidemiological studies were identified through a MEDLINE(R) search of the literature through February 2006. Here, we report on the metabolic characterization of d(x) fruits.

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Quantifying chemical and non-chemical stressors among residents near UGD should be prioritized. On the other hand the outcome of a RCT may not be generalisable to the common practice because of vigorous selection of patients and institutions. Age discrimination in healthcare institutions perceived by seniors and students. P6 induces protective immune responses in animal models and is the target of potentially protective immune responses in humans. The toxin-membrane interactions were analyzed utilising a chip-based technology with immobilized liposomes as artificial cell membranes.

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Failure to recognize posterior column fractures may lead to inappropriate utilization of treatment techniques. Locking an oxidation-sensitive dynamic peptide system in the gel state. Comparative analysis of the cell composition of the infiltrate in malignant lymphoma of the skin However, one variant of the basic pattern, involving the restriction of granule discharge to areas of the terminal plasmalemma situated adjacent to the postsynaptic cells (i.e. Traffic fatalities among victims aged 65 years or older were studied in Metro Dade County between the years 1981 and 1983.

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One-Minute Fish Freshness Evaluation by Testing the Volatile Amine Gas with an Ultrasensitive Porous-Electrode-Capped Organic Gas Sensor System. Following radioiodination of the TPP-based prosthetic group in phosphate buffer, the prosthetic group was purified and coupled to the terminal amine of 15-mer PNA on the solid phase resin.

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Cell clones lacking p21 were not arrested in G1 phase, but continued DNA synthesis and were arrested in G2/M phase following FR901228 treatment. Arsenite, a direct stimulator of p38 MAPK, also led to an increased PPARgamma expression, thereby mimicking the effects of butyrate. Naturally occurring recombination between distant strains of infectious bronchitis virus. Both the NAD- and the NADP-dependent glutamate dehydrogenases were upregulated in the stressed cells despite the sharp decline in the activities of numerous enzymes mediating the tricarboxylic acid cycle and oxidative phosphorylation. Electronystagmographic (ENG) abnormalities included bilateral gaze nystagmus, saccadic pursuit and failure of fixation suppression suggestive of cerebellar-brainstem pathology.

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NtcA interacts with 2-MPA and 2-OG in a similar manner, and it is necessary for heterocyst differentiation induced by 2-MPA. Bordetella pertussis proteins dominating the major histocompatibility complex class II-presented epitope repertoire in human monocyte-derived dendritic cells.

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The role of culture in conservation planning for small or endangered populations. There was a slight but significant increase in serum IgG levels in CyA-treated MRL/1 mice.

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By cross-correlating sustained neuronal activity with the dynamic spectrum of a spectrotemporally rich stimulus ensemble, one obtains an estimate of the STRF. We investigated the HER-2 gene and protein status in several cases of Paget disease of the nipple and vulva by using a chromogenic in situ hybridization assay and immunohistochemistry. In chemical cross-linking of gelatin solutions, two different time scales affect the kinetics of the gel formation in the experiments.

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This study aims at providing guidelines for the optimization of the synthetic design of therapeutic nanomedicines with minimal amounts of photosensitive molecules. Human epidermal growth factor receptor 2 (HER2) has demonstrated significant benefit for gastroesophageal cancers and in the setting of HER2 amplification, trastuzumab in combination with chemotherapy has become the standard of care.

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The results showed that miR-376a was significantly downregulated in NSCLC tissues and cell lines. Identification and developmental expression of a smooth-muscle gamma-actin in postmeiotic male germ cells of mice. To conduct a metasynthesis of human sleep studies that included women aged 50 years and older with breast cancer across chemotherapy treatment. The association between grass pollen counts and total combined rhinoconjunctivitis symptom and medication score (TCS) was based on a post hoc analysis of data collected over six trials and seven grass pollen seasons across North America and Europe, including 2363 subjects treated with grass SLIT-tablet or placebo.

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However, nursing care is usually listed as one category in surveys. The SERPINE2 gene is associated with chronic obstructive pulmonary disease.

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Return to play should be expected in successfully corrected cases that include a collaborative rehabilitation program. Gender specific chronological and morphometric assessment of fetal bladder wall development. PMSG combined with parallel stent provided acceptable short-term results in specific presentation of SRA and TAAA with hostile anatomies in selected high-risk patients with contraindication for standard fenestrated/branched grafts. Our review of past modelling work revealed that most studies employ economic equilibrium modelling and focus on ethanol fuels, especially with maize as feedstock.

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The underlying cause of these findings seems to be explained in part by the direct influences of autonomic reflexes, potentially induced by psychosocial tasks, on the progression of atherosclerosis. The possible functional relevance and its relation to clinical remission and relapse are discussed.

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The relationship between radiation-induced DNA double-strand breaks and cell kill in hamster V79 fibroblasts irradiated with 250 kVp X-rays, 2.3 MeV neutrons or 238Pu alpha-particles. The patients had neither family history nor symptoms of bleeding disorders. At the first stage the department should be equipped with compact, cheap, easily transported, safe and simple in operation, high-quality autonomous specialized automated diagnostic complexes. Transcutaneous bilirubinometry in the management of bilirubinemia in term neonates. While other immune cells are continuously renewed from hematopoietic stem and progenitor cells (HSPC) located in the bone marrow, a lineage of macrophages, known as resident macrophages, have been shown to be self-maintained in tissues without input from bone marrow HSPCs.

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The main sources for article retrieval were the classic bibliographic data bases in the exercise, rehabilitation and physiological science fields such as Index Medicus and Medline. These mutant precursors were imported into mitochondria in vitro as efficiently as the original precursor, indicating that the extension peptide contains sufficient information for the import of the precursor into mitochondria. Hormonal adaptation determines the increase in muscle mass and strength during low-intensity strength training without relaxation

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clathrata, demonstrating an efficient UVB protection of DNA and PS II by screening. These arteries were mounted as ring preparations on a small-vessel myograph for measurement of isometric force development.

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SVD quartets retrieved the correct topology from simulated data, as did SNAPP except in the case of a very unbalanced phylogeny. Quinoline containing acetyl hydrazone: An easily accessible switch-on optical chemosensor for Zn2. If a newly emergent airborne infection should appear, the model could be quickly calibrated to data and intervention options at the early stage of the outbreak. When pseudoaneurysm was in the left side (in one case), supraclavicular incision and posterolateral thoracotomy were adopted to allow the control of both proximal and distal portion of subclavian artery.

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The specificity, purity, isotype, and affinity of the mAbs were characterized and the sandwich ELISA system was established. Atopy is consistently associated with asthma, except in a study in Africa. This comprehensive biochemical characterization of ISWI underscores the evolutionary conservation of the ACF/CHRAC family.

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Colistin dose should be based on the MIC data of a given patient or local antimicrobial sensitivity data to maximize its efficacy. Disruption of adhesive integrity via mutations in genes encoding desmosomal proteins causes an inherited heart disease, arrhythmogenic right ventricular cardiomyopathy (ARVC).

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The lower limit for the normal peak serum cortisol response has been reported to be between 500 and 580 nmol/l. Glycochenodeoxycholate-induced apoptosis is not reduced by augmenter of liver regeneration in the human hepatoma cell line HuH-7.

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lack of knowledge of the causes of mental affection, declined after these interviews. It has been proposed that during the ATP hydrolysis cycle, this tail domain swings against the AAA ring as a lever arm to generate the power stroke. G(z) is a member of the G(i) family of G proteins that is prominently expressed in platelets and brain. A closed-form solution for removing the dead time effects from the poststimulus time histograms. To address perceived inefficiencies in an academic rheumatology practice, a timing/work-flow evaluation was initiated to determine the factors that predict the provider contact time (PCT), i.e., the amount of time that attending physicians spend with patients during an outpatient encounter.

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Phospholipids (PLs), together with hyaluronan and lubricin, are involved in boundary lubrication within human articular joints. Mitochondria from two zones (glomerulosa and fasciculata) of the bovine cortex synthesize aldosterone, but those from glomerulosa are much more active than those from fasciculata. In experiment I, hepatocytes were flow-seeded onto PGA scaffolds and cultured in a flow perfusion system for 24 h. In the current study, we investigated the long-term consequences of briefly exposing the amygdala to elevated levels of CORT with the hypothesis that modulation of the amygdala with CORT results in persistent increases in anxiety-like behavior and viscerosomatic sensitivity. This work aimed to test the antilisterial activity of lactic acid bacteria isolated from Italian salami and study the development of resistance.

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Impact of paraoxonase polymorphism (Q192R) on endothelial function in intact coronary circulation. Epidemiological and experimental evidence so far available suggests that accelerated atherosclerosis can be both the cause and the consequence of RAS. This may provide a humoral mechanism for delayed gastric emptying seen in critical illness. In the long term, this may provide relevant information to dermatologists regarding new strategies for the management of pemphigus clinical condition, allowing possibly a better quality of life for the patients.

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The birth of acknowledgement: Michel Foucault and Werner Leibbrand Furthermore, co-expression of wildtype (wt) or S33A mutated beta-catenin with Tcf-4 did not influence CD97 promoter activity.

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Specific hormones measured included PGF2 alpha, PGE2, TxB2, 6-keto-PGF1 alpha, estrogen, progesterone, and epidermal growth factor. The clinical relevance of MRI identified or confirmed pathology has not been established, and the prevalence of asymptomatic MRI pathology is not known. Dams are universally constructed to change hydrodynamic forces and impound water in urban rivers, but few efforts have been made to expound the impact of dams on the transport of antibiotics in rivers.

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The process led to the development of an enhanced understanding of diagnostic modalities and their limitations with regard to the entities under discussion. Long-term success of a valgus tibial osteotomy is related to the stability over time of the postoperative coronal realignment.

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Studying the etiology of this cancer in south Iran and earlier diagnosis and subsequent better cares are recommended. This novel approach represents a significant improvement in methodology that is rapid and efficient. Artifacts and errors in the electronystagmographic (ENG) evaluation of the vestibular system. Genomic imprinting: a case of inherited hematocrit, radiosensitivity, and antioxidant status in human being, as well as weight of newborn mammals

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Primary malignant melanoma of the orbit arising in a cellular blue naevus. Electromyographic recordings of the M-response showed multiple prolonged potential fluctuations with subnormal amplitudes in grafted cases. Phagosomes containing inert particles have also been shown to transiently acquire Rab7 as they mature. Polymorphisms in the IL-13 and IL-4 receptor alpha genes and allergic rhinitis. In psoriasis and atopic dermatitis, the inflammatory events have neurogenic components and the neuropeptides modify the functions of immuno-active cells in the skin.

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Sera from habitual aborters induce monocyte procoagulant activity: a lymphocyte-dependent event. Furthermore, we determined that selection against mt:CoI(T300I) overlaps with the timing of chemotherapy drugs endoxan lek selective replication of mtDNA in the germarium. A retrospective study of the validity of combined bone scintigraphy (BS) and immunoscintigraphy (IS) using (99m)Tc-labelled murine antigranulocyte antibodies (MAB) and magnetic resonance imaging (MRI) in chronic posttraumatic osteomyelitis. Previous studies indicate that Cathepsin L (CatL) is involved in brain tumour progression. Impact of gestational and lactational phthalate exposure on hypothalamic content of amino acid neurotransmitters and FSH secretion in peripubertal male rats.

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Compared with open surgery, video endoscopy surgery achieved the same efficiency, and had the advantage of reduction of complications, suture removal time and in-surgery blood loss. To derive and validate a clinical prediction rule that identifies patients after myocardial infarction gloclav 375 mg to gm who have preserved left ventricular systolic function. 43 ARMS-patients and 40 FEP-patients were assessed with several clinical and psychosocial measures at study baseline. The locomotor activity of neonatal rats was measured after treatment with serotonin agonists or antagonists.

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Our patients shared typical CINCA characteristics and, sometimes, remarkable perinatal events, peculiar of CIAS1-mutated patients. Here, we found that trophozoites and cysts have different oligomeric species of GlTIM and complexes of GlTIM with other proteins. enterocolitica exhibited excellent growth in rice starch minimal medium and TYSGM-9 medium (with rice starch), but growth glucobay 50 mg acarbose dosage was weak in TYSGM-9 medium (without rice starch). This technique was performed in 16 radical cystectomies, including three pelvic anterior exenterations for female invasive bladder carcinoma, and compared with 23 cases treated with the conventional method. In our series, EBV infection rates are particularly high for nonendemic NPC, although without a statistically significant difference in overall survival, LMP1 and p16 expression was correlated with poorer clinical prognosis.

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The clinical diagnosis of PHT was confirmed in the necropsy study, which ruled out granulomas and discovered only vascular sclerosis and hypertrophy as causative arcoxia 90mg tab factors of the clinical picture. A longitudinal 12-week curriculum with complementary didactic and practical components for final-year students learning how to teach was developed, implemented and evaluated using a multi-level evaluation based on the Kirkpatrick approach with qualitative and quantitative methods.

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In patients with ILD, the D-12, a patient-reported measure of dyspnea severity that requires no reference to activity, is a reliable and valid instrument. Gabapentin possesses good efficacy in long-term treatment of patients with partial and secondarily generalized epileptic seizures. The purpose of hifenac p tablet composition tester this study was to investigate the relationship between obesity and failure of nonsurgical management of pediatric both-bone forearm fractures. Inhibition of RhoA geranylgeranylation by statins decreases membrane GTP-bound active RhoA and subsequent Rho-kinase activity.

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Induction and repair of DNA double-strand breaks in the same dose range as the shoulder of the survival curve. Serum cortisol concentrations increased in pregnant women, but the typical diurnal pattern persisted with accentuazione della trama polmonare in sede ba sale cells nadir levels around midnight and marked elevations during the early morning hours. In this study we show that B-myb expression is required for cells to progress from G1 into S phase and that high levels of ectopic B-myb expression uncoupled from cell cycle regulation rescues cells from p53-induced G1 arrest even in the presence of Waf1/Cip1 transactivation and inhibition of cyclin E/Cdk2 kinase activity.

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These models involve the sum of a normal distribution (to represent failures) and a unimodal distribution (to represent the evoked responses). The interest in two-dimensional liquid chromatography (2D-LC) has been growing atazanavir ritonavir mylan pharmaceuticals up since the last decades.

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Therefore, the patients and their families should be informed adequately during decision making process and quality communication must be provided. At baseline, higher levels of attentional fatigue were associated with younger age, not working, a higher number of comorbidities, and higher levels of trait anxiety. We found a higher percentage of RR phenotype in STEMI and nolicin 400 mg krka croatia HF patients compared to a large control group as well as compared to two other groups of cardiac disease patients.

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The transcriptional starts of both operons were identified and clindahexal 450 mg saw palmetto the quantity of transcript from the mobC-mobE promoter (P1) was at least 10-fold greater than that from the mobA-mobB promoter (P2). The CuPtPd catalyst is designed and synthesized successfully via directly reducing metal ions. Caesarean section rates in Brazil increased by seven percentage points from 1991 to 2006, but factors associated with high rates changed over time.