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Alexan (Spironolactone)
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Spironolactone

Alexan is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. Alexan is used to treat heart failure, high blood pressure (hypertension), or hypokalemia (low potassium levels in the blood). Alexan also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. Alexan is also used to diagnose or treat a condition in which you have too much aldosterone in your body. Aldosterone is a hormone produced by your adrenal glands to help regulate the salt and water balance in your body.

Other names for this medication:
Spironolactone, Aldactone, Aldactazide, Aldactazine, Aldazida, Aldazide, Aldozone, Alexan, Alizar, Carpiaton, Espirone, Espironolactona, Expal, Kespirona, Lanx, Letonal, Osiren, Osyrol, Practon, Prilactone, Spiractin, Spiresis, Spirix, Spiroctan, Spirolang, Spirolon, Spiron, Spirono, Spironolacton, Spironolactona, Spironolakton, Spironolattone, Spirotone, Verospiron, Xenalon,

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Alexan is used to treat certain patients with hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low potassium levels; heart failure; and in patients with edema (fluid retention) caused by various conditions, including liver, or kidney disease. It is also used alone or with other medications to treat high blood pressure. Alexan is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine but reduces the loss of potassium from the body.

High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

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Demonstration and elimination of HbF cells in mothers after the birth of ABO-incompatible children Organisms living outside the tropics measure the changes in the length of the day to adapt to seasonal changes in the environment. Retroperitoneal fibrosis (RF) often presents with characteristic clinical and urographic findings that suggest the diagnosis.

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White matter lesions and T1 changes were identified using NMR and then compared between groups of patients suffering from dementia of the Alzheimer type (DAT), Multiple infarct dementia (MID) and normal controls. High-Performance Polymer Solar Cells Employing Rhodamines as Cathode Interfacial Layers. Rat pups delivered by caesarean section were placed into a water bath, still in patent membranes, at 37 degrees C and variable hypothermic conditions to induce asphyxia and thereafter given to surrogate mothers. HSSP (homology-derived structures of proteins) is a derived database merging structural (2-D and 3-D) and sequence information (1-D).

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Septal perforations 4 mm or less in diameter have been successfully closed in eight out of ten patients with interposition of fascia temporalis. UV-vis spectrophotometry and IR spectroscopy revealed that fly ash shows high sorption efficiency towards humic substances.

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Galectin-1 binds to several glycoproteins on the T cell surface, including CD7. In summary, the authors report the identification of fully validated universal reference genes, optimised primer sequences robust to genomic mutations and simple reference gene pair selection guidelines that enable streamlined qPCR analyses of mRNA abundance in CHO cells with maximum accuracy and precision. Observational study of the impact of short-term duloxetine treatment on body weight in patients with major depressive disorder: a taiwanese perspective.

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Furthermore, for a microcavity pillar with 1.26 mum diameter, single-photon emission is demonstrated by performing photon correlation measurements under pulsed excitation. An analysis of the potential binding energies reveals that this effect is mainly of enthalpic nature. To determine which IIRC scheme was used by retinoblastoma centers worldwide and the percentage of D eyes treated primarily with enucleation versus globe salvaging therapies as well as to correlate trends in treatment choice to IIRC version used and geographic region.

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Studies in recent years investigating the (patho)physiological mechanisms involved in disease aetiology have fostered the development of novel therapeutic concepts for endometriosis, by targeting the hypothalamic-pituitary-gonadal axis, by selective modulation of estrogenic and progestogenic pathways, by inhibiting angiogenesis or by interfering with inflammatory and immunological factors. Clinical checks were performed 2 weeks, 3 months, and then annually after discharge. Only in the minority of patients, T-cell responses correlate with clinical outcome, indicating that other immune cells also gain anticancer activity.

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In additional experiments, we incubated 0.5 units of LDH for 1 h with varying concentrations of PAP, menadione, hydrogen peroxide (H(2)O(2)) or cisplatin. A lottery promotion index was created and hierarchical linear modeling (HLM) was conducted to examine the relationship between extent of lottery promotions and independent variables such as neighbourhood socioeconomic status and city prevalence of lottery ticket purchasing.

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The molecular biological technique-random amplified polymorphic DNA (RAPD) were used. Transport tubules, stained by lumenal GFP, segregated rapidly from COPI-positive membranes after transport activation. The discovery of the peripheral aromatase inhibition as the proper mechanism of action was delayed for both the agents but was relatively more timely for aminoglutethimide. Data from this study clearly reinforce previous findings that Mycoplasma pneumoniae is an etiologic agent of central nervous system infections in humans. Case-control studies augmented by the values of responses and covariates from family members allow investigators to study the association between the response and genetics and environment by relating differences in the response directly to within-family differences in covariates.

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Oral antiplatelet therapy for the management of acute coronary syndromes: defining the role of prasugrel. Using publicly available data, we attempt to estimate the reproductive number (R) of cholera in Mexico, and thereby assess the potential of continued introductions to establish a sustained epidemic. A prospective study to evaluate awareness about medication errors amongst health-care personnel representing North, East, West Regions of India. Effects of nitroglycerin on capacitance vessels: a mechanism for reduction of left ventricular end-diastolic pressure.

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In view of the anatomy of the supraspinatus muscle, of the subacromial space, and of relevant nerves, the rat shoulder should be appropriate for experimental studies on inflammatory conditions in the subacromial space. Growth, signs of avitaminosis and duration of life of Wistar rats receiving semi-synthetic diets containing vitamin A and vitamin B in various proportions

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The exine was lysed by trypsin and was resistant to lysozyme, indicating that protein may be the principal structural material of the outer cyst coat. Thus, the targeting and precise modification of human chromosomal alleles using the DT40 cell shuttle system can be used to define regulatory elements that confer long-range control of gene activity within chromosomal domains. Even though pediatric tonsillectomy is a well accepted treatment for upper airway obstruction or recurrent tonsillar infection, the painful recovery of this operation is unwelcome. Intranasal measurements of CO2 concentrations suggested that these differences were not due to the intranasal distribution of CO2.

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In tumor tissues, VRA09 expression was mainly detected in serous ovarian tumors. Evaluation of the feasibility to integrate traditional Chinese and Western medicine into the educational system

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Small RNAs in the peripheral blood discriminate metastasized from non-metastasized seminoma. A case report is presented of a 58-year-old man who died from accidental hypothermia associated with immersion in cold water while on a farm during warm weather.

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Breast tumors which arise in carriers of CHEK2 mutations seem to be similar to those of breast cancers in the population at large. A partial amino acid sequence in the heavy chain of a rabbit antibody to group C streptococcal carbohydrate. Both diseases are significant among women of childbearing age, and TB, although uncommon in pregnancy, is on the increase. and 1 mg/kg, i.v., respectively), a selective alpha7 n-AChR antagonist. These cases, along with previous reports, suggest resolution may occur, especially in boys under age 12 years.

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Application of traditional Chinese medicine preparation in targeting drug delivery system. Phospholipase A2 activity in platelets of patients with primary thrombocythemia.

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By lowering the hematocrit, the thickness increased and the flow resistance decreased. ArrayExpress service for reviewers/editors of DNA microarray papers. Since monocytes have been shown to be accessory cells for the activation of lymphocytes by mitogens, we investigated the effects of pefloxacin and ciprofloxacin on extracellular interleukin 1 (IL-1) and cell-associated IL-1 from lipopolysaccharide-stimulated human monocytes. Though models of inpatient chaplaincy-psychiatry collaboration likely exist, none are apparent in the literature. The inhibitory effect of cassia oil alone, or in combination with KCl and NaCl were tested in vitro.

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Moreover a calculation of the hospital treatment capacity in the region could serve as a guideline for estimation of the dimensions needed for the medical rescue capacity and medical transport capacity when planning how to deal with a disaster. Correlation of periscreen strip results and white cell count in peritoneal dialysis peritonitis. One potential mode of action for ACE inhibitors in CAD is blood pressure reduction. PDGF-BB treatment in vitro and in vivo resulted in suppression of both steady state and BMP6 inducible hepcidin expression. Especially, the beneficial effects of bisphosphonates (etidoronate, alendronate, and risedronate) to prevent bone loss and fractures have been confirmed by the large-scale, multicenter, double-blind, randomized controlled trials in terms of both primary and secondary prevention.

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In various soft and hard tissues of adult and fetal mice the distribution of mono- and multinucleate cells showing tartrate-resistant acid phosphatase was studied, using enzyme histochemistry on undecalcified plastic sections. Of 150 articles that were reviewed, eight articles were included with three themes in the outcomes for carers: service use, health promotion behaviors and psychological health (such as carer stress, burden or depressive symptoms).

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Most adrenocortical tumors are benign, unilateral, adrenocortical adenomas that are often discovered incidentally. This study suggests that the use of a hemostasis pad in combination with rotatory compression devices is a safe and effective hemostasis strategy after radial artery access. The results imply that the role of singlet oxygen in plant stress regulation and response is more ubiquitous than previously thought. Both pyrogens, on the other hand, act diffusely throughout the CNS when given intrathecally.

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This case report describes the additional value of MRI in a premenarcheal girl with sub-acute right fossa pain. However, it did not improve quality of life, and could have led to macrolide resistance. Because of advances in diagnostic technology and thrombosis research, the assessment of suspected venous gangrene has changed significantly in recent years. It can be administered reliably by all members of the rehabilitation team with different specialties, levels of experience and settings. Mean cyclosporin levels remained stable throughout the 4 weeks of continuous intravenous cyclosporin administration, despite a gradual decrease of the mean cyclosporin dose.

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In agreement with this, the presence of such autoantibodies increase the five-year relative risk for cardiovascular morbidity and mortality three times, both in the general population, and in patients with essential hypertension (2). Prolonged paradoxical response to anti-tuberculous treatment after infliximab.

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Therapeutic hypothermia after cardiac arrest: a retrospective comparison of surface and endovascular cooling techniques. Its binding affinity for HA might have been acquired in the vertebrate lineage. The analysis is used to obtain quantitative estimates of the SD arising from experimental (non biological) intra- and interarray variability, and for a lower threshold for determining whether an individual gene is expressed. The Lower Extremity Functional Scale (LEFS) is a widely used questionnaire to evaluate the functional impairment of a patient with a disorder of one or both lower extremities.

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The role of lactobacilli possessing antagonistic properties in the reproductive tract defense was assessed. Two-month old Wistar rats of both sexes received, as sole drinking liquid, an aqueous solution of ammonium metavanadate (AMV) at a concentration of 0.01, 0.05, 0.15 and 0.30 mg V/ml (corresponding to 0.2, 1, 3 and 6 mM solution) over 4 weeks. In BCa patients, mpMRI appears a promising tool for accurate locoregional staging, predicting tumor aggressiveness and monitoring response to therapy.

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Variability patterns and positively selected sites at the gametophytic self-incompatibility pollen SFB gene in a wild self-incompatible Prunus spinosa (Rosaceae) population. We conclude that lepirudin is an effective anticoagulant during CVVH in patients with HIT II.

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However, GH concentrations in the peaks and nadirs were 2.5-3.5 times greater in the plasma GH profiles of roosters as compared to hens, which resulted in roosters having higher mean GH concentrations. In this paper, we propose that Hippocampal place cells might implement such an error correction mechanism by integrating different sources of information in an approximately Bayes-optimal fashion. Hookworm infections in human and laboratory animals--differences and similarities in immune responses.

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Here, we report cloning of isoforms of sox9 (sox9a and sox9b) from air-breathing catfish Clarias gariepinus, which undergoes an annual reproductive cycle. Multiple vanishing tumours are most uncommon and can resemble other multiple opacities, e.g. A combination of rifampicin and clindamycin gave best results, protecting against three successive challenges over a 28 day perfusion period.

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Fecal oocyst shedding was monitored daily for each mouse using an indirect immunofluorescent assay. Techniques for identification of left ventricular asynchrony for cardiac resynchronization therapy in heart failure. Rational design of a culture medium for the intensification of lipid storage in Chlorella sp. Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75. Milia are a usual omeprazole 40 milligram capsules consultation in dermatologic practice and optimal treatment modalities are not established.

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