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Asiviral (Acyclovir)
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Acyclovir

Asiviral is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Asiviral is converted to an active form by the virus itself, and the virus then uses the active form of Asiviral rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Asiviral into new viral DNA stops the production of the DNA. Virally infected cells absorb more Asiviral than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Asiviral in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Gluconase, Glibenese, Fulgram, Oxcarbazepin, Sanlin, Tranax, Trican, Androfin, Bristamox, Herpesin, Acic, Endoxan, Cipramil, Paxon, Atorva, Fenox, Dycon, Samnir, Pristinex, Nedox, Pantocid, Almetec, Prala, Viralex, Omestad, Practon, Vodelax, Hipen, Emov, Aurex, Infex,

Asiviral buccal is used to treat herpes labialis (cold sores or fever blisters; blisters that are caused by a virus called herpes simplex) on the face or lips. Asiviral is in a class of antiviral medications called synthetic nucleoside analogues. It works by stopping the spread of the herpes virus in the body.

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Short latency somatosensory evoked potential (SSEP) (N20) is a good predictor of poor outcome in postanoxic coma. To investigate the accuracy of predicted time-integrated activity coefficients (TIACs) in peptide-receptor radionuclide therapy (PRRT) using simulated dynamic PET data and a physiologically based pharmacokinetic (PBPK) model. We employ bifurcation analysis to illustrate the stimulus-response behavior of the full model under both voltage regimes. Comparison of the anti-anaphylactic effects of milrinone, sulmazole and theophylline in the rat. Competitive sorption was observed when Kd(pri) was decreased to a certain value depending on solid particle properties.

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injected 10 min before nerve stimulation or formaldehyde exposure. Low-dose staurosporine suppresses proliferation and induces neurites in human prostatic cancer TSU-Pr1 cells. Both selective ETA and dual ETA/ETB improve endothelium-dependent vasodilatation in patients with type 2 diabetes and coronary artery disease.

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This treatment protocol resulted in complete remission of immune-mediated thrombocytopenia in all the dogs, and mycophenolate mofetil was discontinued after several months of therapy in four of the five dogs with no relapses, even when non-steroidal anti-inflammatory drug administration was resumed. Epidemiological investigation established with near certitude that the disease had not been introduced from the outside and it is concluded that the agent may have persisted in the old sheep-house for at least 16 years. The apparent specificity constant, kcat/Km, for HemY was found to be about 12-fold higher with coproporphyrinogen III as a substrate compared with protoporphyrinogen IX as a substrate. The use of BPM enhanced lipid peroxidation and the activity of the antioxidant system of erythrocytes.

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An inhibitor of protein synthesis in cytoplasmic extracts of density inhibited cells. As most bifid condyle subjects have no complaint related to temporamandibular joint(TMJ), the cases are generally diagnosed through incidental radiographic findings. An algorithm to compute optimal genetic contributions in selection programs with large numbers of candidates.

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An alternative oral health provider approach was used to address the low rate of early caries detection, preventative oral care, and access for underserved children. Cellobiase from Termitomyces clypeatus: activity and secretion in presence of glycosylation inhibitors.

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Left atrial enlargement represents a risk factor of atrial fibrillation and stroke. Assessing dementia in people with learning disabilities: the relationship between two screening measures. Under the squared error objective, we show that by varying the training data, a single rectifier neuron admits local minima arbitrarily far apart, both in objective value and parameter space. Biological effect of lead-212 localized in the nucleus of mammalian cells: role of recoil energy in the radiotoxicity of internal alpha-particle emitters.

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Application of Kalman filtering with a novel nearest-symbol constraint enables dynamic tracking of carrier phase and polarization state. Syzygium cumini effectively attenuated the cellular oxidative stress in H9c2 cardiomyoblasts.

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p38 Mitogen-activated protein kinase affects transforming growth factor-beta/Smad signaling in human dental pulp cells. Angiotensin II (Ang II), a major regulator of blood pressure, is also involved in the control of cellular proliferation and hypertrophy and might exhibit additional actions in vivo by modulating the signaling of other hormones. Moreover, the activation by light of several visual cortex areas (including the primary visual cortex) was potentiated by trigeminal pain, demonstrating multisensory integration in these areas. Moreover, increased BMP activity leads to ectopic and supernumerary germ cells. The most important artefacts to be aware of, and to be able to eliminate or minimize, are random noise and blooming, aliasing and motion artefacts.

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British Shorthair, Exotic Shorthair, Foreign Shorthair, Havana Brown, Himalayan, Persian, Ragdoll, and Scottish Fold cats had an increased risk of developing CaOx uroliths, as did male cats and neutered cats. Our findings indicate that the FIM upper-body dressing score on the first day of dressing training is an independent predictor of recovery of upper-body dressing ability after stroke. Biomarkers play an important role in the detection and management of cancer patients. A two-dimension (2D) current and mode calculation provides a simple model to explain the behavior of each mode under different bias conditions.

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A novel hepatitis B virus mutation with resistance to adefovir but not to tenofovir in an HIV-hepatitis B virus-co-infected patient. All samples were analyzed for levels of CA125, HE4, and mesothelin by serum based immunoassays and patients results were compared to final pathology findings. Exposure system and measurements of general health and performance.

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Phenotypic and functional characteristics of bovine T lymphocytes. After subsequent dissociation of the particles from the receptors within the endosomes, the ligands were transported to secondary lysosomes, the receptors were transported to a trans-Golgi system. The publication process itself was the major cause of publication bias in genetic epidemiology. The expression modes of several differentially expressed proteins were confirmed by Western blot and qRT-PCR. Study of the growth of the Bacillus subtilis membrane by means of flagella distribution

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Genetic and cellular basis of anti-DNA antibody synthesis in systemic lupus erythematosus of New Zealand mice. After successful ablation of the slow pathway considered responsible for the supraventricular tachycardia, an Amplatzer closure device was utilized and the PFO was successfully closed during the same procedure. latifolia) across Yellowstone National Park influences initial pine recruitment after stand-replacing fire with tremendous population, community, and ecosystem consequences. Although intraocular metastases are the most frequent intraocular tumour, they are not a frequent cause of consultation.

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Erythema ab igne caused by chronic heat exposure presents as a net-like hyperpigmentation of the skin. Stratum 1 includes patients in whom active surveillance is associated with a low risk of disease progression. The results also indicated that an object whose orientation was parallel to its motion path strengthened the spatiotemporal integration of local motion signals along a straight motion path, resulting in the perception of streaming.

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Streptococcus mutans in plaque from conventional and from non-gamma-2 amalgam restorations. NS5B nonnucleoside inhibitors inhibited dose dependently the synthesis of single-stranded RNA but not double-stranded RNA. They give rise to neurons and glial cells in response to injury and utilization of endogenous stem cells in the treatment of nervous system diseases is important strategy in neurogenesis. More RCT with standardization of symptom scores and medications are needed in order to contribute further to this subject. Potential uses of economic evaluation include the development of public reimbursement lists, price negotiation, the development of clinical practice guidelines, and communicating with prescribers.

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Using five commercially available vaccines, groups of dogs were vaccinated against Lyme borreliosis and followed for 13 months. The new salt formulations clopidogrel where approved based on pharmacokinetic measurements of the inactive prodrug on few healthy volunteers, without any other medication. This study examined 10 year trends in functional capacity by gender, age, and education among elderly Finns aged 65-84 years, focusing on difficulties in basic activities of daily living (BADL).

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Long-term evaluation of HIV antigen and antibodies to p24 and gp41 in patients with hemophilia. There is, however, little information available about sample size requirements for such phase II trials and rarely enough patients in single studies to make robust estimates. These should provide useful tools for delineating the physiological roles of these receptors, specifically labeling certain receptors, and developing therapeutically interesting compounds targeted towards specific physiological events.

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Apoptosis of testicular germ cells induced by exogenous glucocorticoid in rats. Sequencing of the recombinant AFP showed that it had a 17-amino-acid extension N-terminal to the 129-amino-acid mature AFP that began where signal peptide cleavage should occur according to current algorithms. The assimilation of nucleic acid precursors by intact cells and protoplasts of the blue-green alga anacystis nidulans. During rectal cancer treatment, patients receive neoadjuvant chemoradiation (CRT) irradiation which can exacerbate the hematologic toxicity (HT) via incidental irradiation of the pelvic bone marrow (PBM) during myelosuppressive postoperative chemotherapy. Adenosine, apyrase, and prostaglandin E(1) produced slight inhibition.

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A total of 106 students in the classes of 1992-1994 at the Clinical Campus at Binghamton of the State University of New York Health Science Center at Syracuse College of Medicine were surveyed at the beginning and end of their third year about specialty interests and attitudes toward medical care practices. Pertussis is a highly contagious disease caused by Bordetella pertussis. Glucocorticoids inhibit IL-1 and IL-1 receptor antagonist (IL-1ra) expression, Th1 cytokines stimulate both and Th2 cytokines stimulate IL-1ra and inhibit IL-1.

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Significance of arthrography and computed tomography in the assessment of internal derangement of the temporomandibular joint. We found that injection of an IGF-I antisense oligonucleotide in the inferior olive elicited a complete inhibition of conditioned eye-blink learning in freely moving rats. The effect of osteoarthritis on 1-year risk of ischemic heart disease following total knee arthroplasty.

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Clinical experience highlights the wide heterogeneity of primary prostate cancer (PPCa), even when potentially related to the same grade and stage. The second category consists of a heterogeneous group of compounds aiming to decrease fat mass by increasing energy expenditure or by redistributing adipose tissue. The global increase of spinal infections is concomitant with the rise of its risk factors, including HIV/AIDS, diabetes mellitus, intravenous drug use, advanced age, and gunshot wounds to the spine. The null hypothesis was rejected: materials showed different tensile bond strengths. Preliminary data suggest that the administration of creatine may be beneficial to patients with traumatic brain injury.

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Chemotherapy with carboplatin and etoposide in combination with radiotherapy induced complete remission of the tumors. Furthermore, ROCK1 deficiency enhanced the inhibitory effects of diphenyleneiodonium (an inhibitor of NADPH oxidase) on ROS generation and caspase 3 activation induced by doxorubicin. Sprague-Dawley rats were used to study the effects of ibotenic acid lesions of the anterior (A.Th.) and the dorsomedial (MD) thalamic nuclei on learning and memory. Our comparison study shows that 7-T DCE-MRI provides simultaneous high temporal and spatial resolution that is significantly improved compared with lower field strengths, but further technical improvements are necessary to overcome B1 inhomogeneity problems at 7 T to fully unfold the potential of breast MRI at 7 T.

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C57BL/6J (C57) and DBA/2J (DBA) mice exhibit progressive high-frequency hearing loss. Effect of vascular activity in the determination of rate constants for the uptake of 18F-labeled 2-fluoro-2-deoxy-D-glucose: error analysis and normal values in older subjects. Tray agglutination and mixed antiglobulin reaction tests were used for the comparison of sperm-agglutinating antibodies in sera, in ovulatory cervical mucus, and in seminal plasma. Using a gel retardation assay, NdgR was found to bind the upstream region of gylC, working as a repressor. To examine the associations of socioeconomic status (SES) with dietary intake and health related factors in pregnant women.

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