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Ketokonazol (Ketoconazole)
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Ketoconazole

Ketokonazol is active against Candida spp., and Cryptococcus neoformans. However, its activity is limited compared to that of fluconazole and itraconazole. Furthermore, due to its limited penetration to cerebrospinal fluid, it is clinically ineffective in meningeal cryptococcosis. Its activity against the dimorphic moulds, Histoplasma capsulatum, Blastomyces dermatitidis, Coccidioides immitis, Sporothrix schenckii, Paracoccidioides brasiliensis, and Penicillium marneffei is favorable. However, fluconazole and itraconazole are at least as effective as Ketokonazol against these fungi and are safer. Thus, Ketokonazol remains as an alternative second-line drug for treatment of infections due to dimorphic fungi. Ketokonazol is not recommended for treatment of meningeal infections due to Histoplasma capsulatum, Blastomyces dermatitidis, and Coccidioides immitis due to its limited penetration to cerebrospinal fluid. Ketokonazol is also active against Pseudallescheria boydii and is a good alternative for treatment of pseudallescheriasis. It is also effective in pityriasis versicolor. Ketokonazol has practically no activity against Aspergillus spp., Fusarium spp., and zygomycetes order of fungi.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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Ketokonazol is used to treat serious fungal or yeast infections, such as candidiasis (thrush, oral thrush), blastomycosis (Gilchrist's disease), coccidioidomycosis (Valley fever, San Joaquin Valley fever), histoplasmosis (Darling's disease), chromoblastomycosis (chromomycosis), or paracoccidioidomycosis (South American blastomycosis, Lutz-Splendore-Almeida disease). This medicine works by killing the fungus or yeast, or preventing its growth.

Ketokonazol is also used to treat parasitic fungal infections on the skin (such as athlete's foot or ringworm) that cannot be treated with topical medicine or griseofulvin, or for patients who cannot take griseofulvin.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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Integrin alpha(v)beta(3)-negative MCF-7 cells exert more radiosensitivity than MDA-MB-435 cells. We describe a series of patients who developed purpuric allergic contact dermatitis to textile dyes and resins in their personal clothing. Paracetamol-induced 5-oxoproline intoxication should be considered as a cause of HAGMA in patients with female gender, sepsis, impaired renal function or uncontrolled type 2 diabetes mellitus, even when other more obvious causes of HAGMA such as lactate, ketones or renal failure can be identified. A blocking effect was less frequently exerted by carbohydrate-free gp70 and p15(E) antigens.

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Significance of nuclear morphometry as a diagnostic tool in fine-needle aspirates of the liver. Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines.

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A series of 9-(acylamino)doxycycline derivatives has been prepared. Success in the domain of work is a salient developmental task of adulthood and a key indicator of adaptive function in the evaluation of health and psychopathology. Riluzole induced one or more adverse effects in 50.3 per cent of patients. Measurement of immune complexes with the liquid phase C1q binding assay: ten years experience in a routine diagnostic laboratory.

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Vibrational spectroscopy and analysis of pseudo-tetrahedral complexes with metal imido bonds. Adams-Oliver syndrome is a rare congenital anomaly complex characterized by aplasia cutis congenita (ACC) and terminal transverse limb defects. Specialty-specific trends in the prevalence and distribution of outpatient surgery: implications for payment and delivery system reforms. Variability in neuronal firing exhibits sufficient uncertainty so that a simple average firing frequency code is probably inadequate for most nervous system signalling. A longitudinal study of economies of scale in the hospital industry.

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The results provide two coexpression clusters across the three regions, a Hif-1a coexpression cluster and a cluster around the cell death-associated transcripts Casp3, Capn1, Capn2, and Capns1. The objective of our study was to evaluate the clinical utility of performing contrast-enhanced sonography before percutaneous biopsy of focal liver lesions. The author discusses the environment which affects man throughout life.

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A phase II study of high-dose hydroxyurea and dacarbazine (DTIC) in the treatment of metastatic malignant melanoma. To investigate the ability of anthrax toxin lethal factor (LF) to translocate foreign proteins into the cytosol of eukaryotic cells and to characterize the structural requirements of this process, fusion proteins containing a portion of LF and the catalytic domains of either diphtheria toxin or Shiga toxin were constructed.

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Unilesional mycosis fungoides successfully treated with imiquimod. A biomechanical comparison of a novel spondylolysis repair technique method to established spondylolysis repair constructs accompanied by a case series of 5 adolescent patients with spondylolysis treated with this technique. Prolonged exposure of rabbit ASMCs to muscarinic agonists decreases the expression of smooth muscle specific marker proteins, down-regulates muscarinic receptors and decreases ASMC contractile responsiveness. Mutagenesis of hY1 RNA showed that the binding site for Ro60 protein, which is required for Ro RNP assembly, is not essential for DNA replication.

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To develop a set of indicators for diagnosis and treatment of patients with non-small cell lung cancer, we systematically achieved consensus on the basis of a national, multidisciplinary, evidence-based guideline and the opinions of professionals and patients. Moderate airway obstruction occurred frequently when effort was taken to minimise leak. Quantification of the complement receptor function on polymorphonuclear leukocytes: its significance in patients with systemic lupus erythematosus.

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Chest wall reconstruction following resection of large primary malignant tumors. In this study, it was observed that rose oil had physiological and psychological relaxation, analgesic and anti-anxiety effects. On reaction with DPBA, the alpha-AA moiety of N-terminal gamma-glutamyl peptides is also derivatized as demonstrated by the formation of a glutathione boroxazolidone. Ischemia-reperfusion injury to the retinas in albino Lewis rats was induced by elevated intraocular pressure (IOP) through cannulation of the anterior chamber with a needle connected to a saline column delivering a pressure of 110 mm Hg.

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Evaluation of conventional hemi nested PCR analysis for fetal RHD determination in maternal plasma Controlled field trial with dried sorbed paratyphoid B and typhoid vaccines. Research advance on signaling pathways and protein metabolism for skeletal muscle disuse atrophy

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The glycolytic flux was investigated in the thermosensitive Saccharomyces cerevisiae adenylate cyclase mutant cdc35-1. In order to identify the complexities and dynamics of the proteomes expressed by cells, tissues, or organisms, techniques providing improved analytical sensitivity, throughput, and dynamic ranges are still demanded. Collectives studied and rates of breast feeding in the maternity ward

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A prospective study of periodontal disease and risk of rheumatoid arthritis. We describe a young male with definite primary antiphospholipid syndrome who developed insidious diffuse pulmonary infiltrates. A protocol for protein analysis using two-dimensional difference gel electrophoresis (2D-DIGE) is described. These data suggest that the coordinated regulation of stress kinases by GSTp, as reflected by increased p38, ERK, and nuclear factor kappaB activities together with suppression of JNK signaling, contributes to protection of cells against reactive oxygen species-mediated death.

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Here we present the results of a study of 10 chimpanzees (Pan troglodytes). High Prevalence of Neuropathic Pain Component in Patients with Low Back Pain: Evidence from Meta-Analysis.

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The mutagenicity of dacarbazine was assayed in an in vivo test utilizing mouse bone marrow cells. The new isolates Clostridium roseum C and Clostridium saccharoperbutylacetonicum PF produced hydrogen with yields of 2.0 mol H2 mol-1 hexose at 40 and 60 g L-1 molasses and 2.1 mol H2 mol-1 hexose at 40 gL-1 molasses, respectively. Fundus exam showed pale and swollen optic nerve in the left eye, and temporal artery biopsy showed diffuse and extensive calcification at the internal elastic lamina and media. Estimation of glycaemic index of peach palm (Bactris gasipaes) cooked fruits and chips, and pitahaya (Hylocereus spp.) pulp.

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This study suggested that GP with a suitable hydrophobicity, relatively lower burst release, and higher PA was the most promising lipid material of SLN for oral delivery of proteins. pylori) infection may predispose IBS patients to functional dyspepsia. We report on a case of hepatitis B virus-related polyarteritis nodosa (PAN) in a 4-year-old Turkish boy who was first admitted because of severe arterial hypertension. Anti-tubercular Activity of Pyrazinamide is Independent of trans-Translation and RpsA. ECC may be implemented in the current VCC systems by means of a software upgrade.

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The aim of the present study is to evaluate the efficacy of a low FODMAP diet and a specific carbohydrate diet (SCD) conducted for 3 months on symptoms and to evaluate the deficiencies of vitamin D and folic acid in patients affected by IBS, matching the Rome IV criteria. This report describes a novel approach of accessing the superficial veins of the upper extremity for the treatment of pulmonary emboli (PE) with an ultrasound enhanced thrombolytic infusion catheter. In addition, extensive studies have been directed to ifa norex 50 mg information about measure ion channel activity, structure-function relationships, as well as many other biophysical and biochemical properties. The order of their potencies were as follows: Phenylephrine greater than or equal to NE greater than or equal to angiotensin II greater than PGF2 alpha greater than or equal to 5-HT much greater than KCl. Light generation and harvesting in a van der Waals heterostructure.

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